Process of preparing mixed heparin salts

Details Process of preparing mixed heparin salts Process of preparing mixed heparin salts

1974-04-10

1979-09-18

Raymond, Richard

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424183, C08B 3710

Patent

active

041683773

ABSTRACT:
Mixed or simple heparin salt having a reduced amount of a selected metal ion alone or with another metal ion in a mixed heparin. A heparin salt having a reduced sodium content being essentially sodium free and having a selectively high calcium or other selected salt content. A process for making these heparin salts by reaction with the selected metal salt, including, optionally, dialysis or precipitation. A typical heparin salt is a calcium heparin essentially free of sodium (like containing less than about 1% by weight of sodium), or mixed calcium-sodium heparin with a limited, predetermined content of sodium. Drug compositions containing these heparin salts and a pharmaceutical carrier. The drugs made from these heparin salts are useful as anti-coagulants.

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