Thioalkylthio cephalosporin derivatives

Details Thioalkylthio cephalosporin derivatives Thioalkylthio cephalosporin derivatives

1991-07-12

1993-05-25

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514201, 540221, 540225, 540227, C07D50124, A61K 31545

Patent

active

052140377

ABSTRACT:
A novel thioalkylthio cephalosporin antibiotic compound of formula I: ##STR1## wherein Acyl is C.sub.1 -C.sub.12 acyl; Het is optionally substituted monocyclic heteroaromatic group containing one or more hetero atoms; R.sup.1 is a single bond or C.sub.1 -C.sub.4 alkylene; R.sub.2 is a straight or branched C.sub.1 -C.sub.4 alkylene; X is a sulfur atom or sulioxide group; and Y is a hydrogen atom or methoxy group, or a pharmaceutically acceptable salt or an amino-, carboxy- and/or hydroxy-protected derivative thereof, a formulation containing the same and a method for treating bacterial infections.

REFERENCES:
patent: 4921953 (1990-05-01), Yokoo et al.

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