Valproic acid ester with antiepileptic and anticonvulsant activi

Details Valproic acid ester with antiepileptic and anticonvulsant activi Valproic acid ester with antiepileptic and anticonvulsant activi

1980-06-02

1984-04-10

Garner, Vivian

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424317, 560263, 562606, C07C 6928, A61K 3122

Patent

active

044421249

ABSTRACT:
The compound pivaloyloxymethyl 2-propyl-pentanoate of formula I: ##STR1## is described. The process for the preparation consists of reacting 2-propyl-pentanoic acid with chloromethyl pivalate and isolating the pivaloyloxymethyl 2-propyl-pentanoate from the reaction mixture. Pharmaceutical compositions with antiepileptic and anticonvulsant activity containing an effective amount of compound I are described.

REFERENCES:
patent: 3076839 (1963-02-01), Webb
patent: 3148207 (1964-09-01), Weinkauff et al.
patent: 3325361 (1967-06-01), Meunier
patent: 3993684 (1976-11-01), Dunnawant et al.

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