N-Carbobenzoxy-N'-(2-nitrophenyl)-2-piperazine carboxylic acid

Details N-Carbobenzoxy-N'-(2-nitrophenyl)-2-piperazine carboxylic acid N-Carbobenzoxy-N'-(2-nitrophenyl)-2-piperazine carboxylic acid

1977-09-22

1979-02-06

Tovar, Jose

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544346, 544389, 424250, C07D24118, C07D24106

Patent

active

041385675

ABSTRACT:
Compounds of the formula ##STR1## wherein R is hydrogen (lower)alkyl, phen(lower)alkyl, benzoyl(lower)alkyl, or p-halobenzoyl(lower)alkyl; R.sup.1 is hydrogen or (lower)alkyl; R.sup.2 is hydrogen, (lower)alkyl, (lower)alkoxy, chlorine, fluorine, trifluoromethyl, or amino in the 7-, 8-, or 9-position; R.sup.3 is hydrogen, or (lower)alkyl; and R.sup.4 is hydrogen, (lower)alkyl, (lower)alkoxy, chlorine, fluorine, or trifluoromethyl in the 7-, 8-, or 9-position; or the non-toxic acid addition salts thereof; exert a hypotensive effect in hypertensive animals.

REFERENCES:
patent: 4032639 (1977-06-01), Freed
patent: 4089958 (1978-05-01), Freed et al.

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