Hexahydrocarbazole containing alkylaminoamide compounds, pharmac

Details Hexahydrocarbazole containing alkylaminoamide compounds, pharmac Hexahydrocarbazole containing alkylaminoamide compounds, pharmac

1986-07-10

1988-11-01

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548439, A61K 3140, C07D20988

Patent

active

047820756

ABSTRACT:
Novel alkylaminoamides of the formula ##STR1## wherein R is selected from the group consisting of (a) alkyl of 1 to 8 carbon atoms, (b) cycloalkyl of 3 to 7 carbon atoms optionally substituted with phenyl, (c) aryl of 6 to 14 carbon atoms optionally substituted with at least one member of the group consisting of halogen, --CF.sub.3, alkyl of 1 to 6 carbon atoms, -- NO.sub.2 and cycloalkyl of 3 to 7 carbon atoms, (d) aralkyl of 7 to 14 carbon atoms and (e) ##STR2## Z is --(CH.sub.2).sub.n -- optionally substituted by an alkyl of 1 to 6 carbon atoms, n is an integer from 1 to 6, Y is --(CH.sub.2).sub.n -- or ##STR3## and their non-toxic, pharmaceutically acceptable acid addition salts having remarkable anti-oedematous and anti-inflammatory activity.

REFERENCES:
patent: 4254134 (1981-03-01), Fliedner, Jr.

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