Agglutination immunoassay of immune complex with RF or Clq

Chemistry: physical processes – Physical processes – Crystallization

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232306, 1951035A, 424 1, 424 8, 424 12, G01N 3114, G01N 3316

Patent

active

041382137

ABSTRACT:
A method of determining Ab:Ag complex in a biological fluid sample comprising adding to the sample a solution of RF or Clq and a known quantity of a material, such as immunoglobulin-coated polystyrene particles, which is caused to agglutinate on contact with RF or Clq, and detecting the amount of material which is not agglutinated.

REFERENCES:
patent: 3658982 (1972-04-01), Reiss
patent: 3689632 (1972-09-01), Mizushima
J. S. Cowdery, Jr., J. Immunology, 114 (1), 5-9 (1975).
U. E. Nydegger, J. Clin. Invest., 54, 297-309 (1974).
Chemical Abstracts, 74: 2303c (1971).
Chemical Abstracts, 81: 36322t (1974).

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