Human Reg protein

Details Human Reg protein Human Reg protein

1996-10-11

1998-11-17

Stucker, Jeffrey

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 691, 4351723, C07H 2104, C12Q 168, C12P 2106, C12N 1500

Patent

active

058378413

ABSTRACT:
The present invention provides a polynucleotide (reg I.gamma.) which identifies and encodes a novel human Reg I.gamma.. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding human Reg I.gamma.. The invention also provides for the use of purified Reg I.gamma. and its agonists in the production of recombinant proteins and in pharmaceutical compositions for the treatment of diseases associated with the expression of Reg I.gamma.. Additionally, the invention provides for the use of Reg I.gamma. antagonists and inhibitors, including antisense molecules to reg I.gamma. in pharmaceutical compositions for the treatment of diseases associated with the expression of Reg I.gamma.. The invention also describes diagnostic assays which utilize the polynucleotide to hybridize with the transcripts and/or genomic DNA encoding Reg I.gamma. and anti-human Reg I.gamma. antibodies which specifically bind to Reg I.gamma..

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Database EMBL, entry HSZZ19915, Accession No. AA314779, Apr. 18, 1997, XP-00205345.

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