Nucleic acids molecules encoding Caspase-8h and Caspase-8i

Details Nucleic acids molecules encoding Caspase-8h and Caspase-8i Nucleic acids molecules encoding Caspase-8h and Caspase-8i

1997-02-27

1998-11-17

Stucker, Jeffrey

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

530300, 530350, C07H 2102, A61K 3800, C07K 100

Patent

active

058378375

ABSTRACT:
The present invention concerns the Caspase-8h gene and the Caspase-8i gene. The Caspase-8h gene encodes a 220 amino acid polypeptide having two FADD death effector domains. The Caspase-8i gene encodes an 81 amino acid polypeptide having one FADD death effector domain. The invention encompasses nucleic acid molecules encoding Caspase-8h or Caspase-8i, vectors containing these nucleic acid molecules, and cells harboring such vectors.

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