Method of using pentoxifylline for treating inflammation

Details Method of using pentoxifylline for treating inflammation Method of using pentoxifylline for treating inflammation

1989-08-07

1990-12-04

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514262, A01N 4390, A61K 3152

Patent

active

049754327

ABSTRACT:
A combination product containing (A) on the one hand a xanthine derivative of the formula ##STR1## in which one of the radicals R.sup.1 and R.sup.3 represents a straight-chain alkyl, .omega.-1)-oxoalkyl or (.omega.-1)-hydroxyalkyl group having 3 to 8 carbon atoms, and the two other radicals R.sup.2 and R.sup.3, or R.sup.1 and R.sup.2 represent straight-chain or branched alkyl groups having 1 to 8 carbon atoms in the position of R.sup.1 and R.sup.3 and 1 to 4 carbon atoms in the position of R.sup.2, the maximum total of carbon atoms in these two alkyl substituents being 10, or of the formula ##STR2## in which R represents an alkyl radical having 1 to 4 carbon atoms, or prodrug forms of the oxoalkylxanthines of the formula I and II or of the hydroxylalkylxanthine of the formula I, or its metabolites, and

REFERENCES:
patent: 4558051 (1985-12-01), Sunshine et al.
patent: 4853386 (1989-08-01), Friebe et al.
patent: 4880791 (1989-11-01), Weithmann et al.
Sakurai et al., Abstract from the Japanese Journal of Pharmacology, vol. 33, 1983.
Remien et al., Abstract from the Archives of Pharmacology, vol. 293, 1976.
Rote Liste, 1987, No. 36056.
Gallenkamper et al., Br. J. Pharmac., 81, 1984, pp. 575-581.

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