Reverse-turn mimetics and methods relating thereto

Details Reverse-turn mimetics and methods relating thereto Reverse-turn mimetics and methods relating thereto

1995-10-27

1999-07-27

Achutamurthy, Ponnathapura

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D47100, C07D48700, G01N 33543

Patent

active

059292377

ABSTRACT:
Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetics have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetics of this invention are also disclosed, as well as methods for screening the same to identify biologically active members.

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