Method for treating diseases mediated by cellular proliferation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

5142288, 5142295, 514277, 514300, 514302, A61K 3152, A61K 31535, A61K 3151, A61K 3144

Patent

active

059290811

ABSTRACT:
There is disclosed a method for:

REFERENCES:
Brown et al., The New England Journal of Medicine, "Regression of Coronary Artery Disease As A Result of Intensive Lipid-Lowering Therapy In Men With High Levels Of Apolipoprotein B", vol. 323, No. 19, pp. 1289-1298, 1990.
Casscells et al., Proc. Natl. Acad. Sci. USA, "Elimination Of Smooth Muscle Cells In Experimental Restenosis: Targeting Of Fibroblast Growth Factor Receptors", vol. 89, pp. 7159-7163, 1992.
Ferns et al., Science, "Inhibition Of Neointimal Smooth Muscle Accumulation After Angioplasty By An Antibody To PDGF", vol. 253, pp. 1129-1132, 1991.
Ferrara, et al., J. Clin. Invest., "Expression Of Vascular Endothelial Growth Factor Does Not Promote Transformation But Confers A Growth Advantage In Vivo To Chinese Hamster Ovary Cells", vol. 91, pp. 160-170, 1993.
Fingerle et al., Proc. Natl. Acad. Sci. USA, "Rose Of Platelets In Smooth Muscle Cell Proliferation And Migration After Vascular Injury In Rat Carotid Artery", vol. 86, pp. 8412-8416, 1989.
Folkman, et al., Nature, "Induction Of Angiogenesis During The Transition From Hyperplasia To Neoplasia", vol. 339, pp. 58-61, 1989.
Harris, Jr., Arthritis and Rheumatism, "Recent Insights Into The Pathogenesis Of The Proliferative Lesion In Rheumatoid Arthritis", vol. 19, No. 1, pp. 68-72, 1976.
Hori et al., Cancer Research, "Suppression Of Solid Tumor Growth By Immunoneutralizing Monoclonal Antibody Against Human Basic Fibroblast Growth Factor", vol. 51, pp. 6180-6184, 1991.
Kane et al., JAMA, "Regression Of Coronary Atherosclerosis During Treatment Of Familial Hypercholesterolemia With Combined Drug Regimens", vol. 264, No. 23, 1990.
Kim et al., Nature, "Inhibition Of Vascular Endothelial Growth Factor-Inducted Angiogenesis Suppresses Tumor Growth in vivo", vol. 362, pp. 841-844, 1993.
Lindner et al., Proc. Natl. Acad. Sci. USA, "Proliferation Of Smooth Muscle Cells After Vascular Injury Is Inhibited By An Antibody Against Basic Fibroblast Growth Factor", vol. 88, pp. 3739-3743, 1991.
McLeskey et al., Cancer Research, "Fibroblast Growth Factor 4 Transfection Of MCF-7 Cells Produces Cell Lines That Are Tumorigenic And Metastatic in Ovariectomized Or Tamoxifen-Treated Athymic Nude Mice", vol. 53, pp. 2168-2177, 1993.
Morisaki et al., Atherosclerosis, "Cell Cycle-Dependent Inhibition Of DNA Synthesis By Prostaglandin I.sub.2 In Cultured Rabbit Aortic Smooth Muscle Cells", vol. 71, pp. 165-171, 1988.
Nabel et al., J. Clin. Invest., "Recombinant Platelet-Derived Growth Factor B Gene Expression In Porcine Arteries Induces Intimal Hyperplasia In Vivo", vol. 91, pp. 1822-1829, 1993.
Pickering et al., J. Clin. Invest., "Proliferative Activity In Peripheral And Coronary Atherosclerotic Plaque Among Patients Undergoing Percutaneous Revascularization", vol. 91, pp. 1469-1480, 1993.
Popma et al., Circulation, "Clinical Trials Of Restenosis After Coronary Angioplasty", vol. 84, No. 3, pp. 1426-1436, 1991.
Ross, Nature, "The Pathogenesis Of Atherosclerosis: A Perspective for the 1990s", vol. 362, pp. 801-809, 1993.
Ross et al., Science, "Localization Of PDGF-B Protein In Macrophages In All Phases Of Atherogenesis", vol. 248, pp. 1009-1012, 1990.
Sano et al., J. Clin. Invest., "Coexpression Of Phosphotyrosine-Containing Proteins, Platelet-Derived Growth Factor-B, And Fibroblast Growth Factor-1 In Situ In Synovial Tissues Of Patients With Rheumatoid Arthritis And Lewis Rats With Adjuvant Or Streptococcal Cell Wall Arthritis", vol. 91, pp. 553-565, 1993.
Sano et al., J. Cell Biology, "Detection Of High Levels Of Heparin Binding Growth Factor-1 (Acidic Fibroblast Growth Factor) In Inflammatory Arthritic Joints", vol. 110, pp. 1417-1426, 1990.
Shimokado et al., Cell, "A Signifigant Part Of Macrophage-Derived Growth Factor Consists Of At Least Two Forms Of PDGF", vol. 43, pp. 277-286, 1985.
Tzeng et al., Blood, "Platelet-Derived Growth Factor Promotes Human Peripheral Monocyte Activation", vol. 66, pp. 179-183, 1985.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for treating diseases mediated by cellular proliferation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for treating diseases mediated by cellular proliferation , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for treating diseases mediated by cellular proliferation will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-879010

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.