Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-12-23
1994-05-17
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514326, 514365, 514374, 514381, 514422, 514459, 514925, A61K 3155, A61K 31445, A61K 31425, A61K 3142
Patent
active
053128184
ABSTRACT:
A method is provided for protecting against and/or treating ulcerative gastrointestinal conditions, including anti-inflammatory drug-induced gastrointestinal ulcers, using a thromboxane A.sub.2 receptor antagonist. In addition, a combination is provided which includes a thromboxane A.sub.2 receptor antagonist and an anti-inflammatory agent which combination may be used to treat inflammatory conditions, such as arthritis, while inhibiting formation of and/or treating gastrointestinal ulcers.
REFERENCES:
patent: 4182854 (1986-04-01), Hall et al.
Mochizuki et al. Scand. J. Gastroenterol., 24(Supp. 162), 194-7 (1989).
Gervasi et al, Int. J. Tiss. Reac., V(3), 253-56 (1983).
Aberg A. K. Gunnar
O'Keefe Eugene H.
Ogletree Martin L.
Rubin Bernard
E. R. Squibb & Sons Inc.
Hook Gregory
Rodney Burton
Waddell Frederick E.
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