Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Patent
1995-06-02
1999-07-27
Eisenschenk, Frank C.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
4241531, 4241731, 4241821, 4241851, 4241921, 435 697, 514 12, 530324, 5303871, A61K 39395, A61K 3816, C12N 1562, C07K 14705
Patent
active
059286431
ABSTRACT:
Polypeptides and proteins comprising the CD2-binding domain of LFA-3 are disclosed. DNA sequences that code on expression for those polypeptides and proteins, methods of producing and using those polypeptides and proteins, and therapeutic and diagnostic compositions are also disclosed. Deletion mutants unable to bind CD2 and methods for their use are also disclosed. In addition, fusion proteins which comprise the CD2-binding domain of LFA-3 and a portion of a protein other than LFA-3, DNA sequences encoding those fusion proteins, methods for producing those fusion proteins, and uses of those fusion proteins are disclosed.
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Miller Glenn T.
Rosa Margaret D.
Wallner Barbara P.
Biogen Inc.
Eisenschenk Frank C.
Kaplan Warren A.
Rabin Evelyn
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