Steroid-20-carboxylic acid compounds and a process for their pro

Details Steroid-20-carboxylic acid compounds and a process for their pro Steroid-20-carboxylic acid compounds and a process for their pro

1982-09-24

1985-05-28

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603973, C07J 900

Patent

active

045199493

ABSTRACT:
New .DELTA.1,4,9(11)-pregnatrien-3-one-2o-carboxlic acid compounds are described, corresponding to general formula I below: ##STR1## in which X represents halogen, particularly chlorine or bromine or NH.sub.2. There is also described the process for producing compounds corresponding to general formula I by dehydrating the corresponding saturated starting compounds hydroxylated in the 11-position to form the 9(11)-ene-bond, after which the product obtained is, if desired, subjected to chemical transformation into the end products corresponding to general formula I. In particular, it is possible to carry out formation of the 20-acid halides and dehydration in the 9(11)-position in a single process step.

REFERENCES:
patent: 4252730 (1981-02-01), Krbechek

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