Substituted trifluoromethylphenyltetrahydropyridines having a cy

Details Substituted trifluoromethylphenyltetrahydropyridines having a cy Substituted trifluoromethylphenyltetrahydropyridines having a cy

1984-07-16

1986-07-22

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3144

Patent

active

046020241

ABSTRACT:
The invention relates to 4-(-3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridines of formula ##STR1## in which R represents a cyano, acetyl or cycloalkyl group of from 3 to 7 carbon atoms and Alk represents a straight or branched alkylene of from 1 to 4 carbon atoms, as well as to the salts thereof, having an anorectic activity, to a process for preparing same and to pharmaceutical compositions containing said compounds, useful in the treatment of obesity.

REFERENCES:
patent: 3072648 (1963-01-01), Bonvicino
patent: 3125488 (1964-03-01), Biel
patent: 3284457 (1966-11-01), Beschke et al.
patent: 3626066 (1971-12-01), Helsley
patent: 3627775 (1971-12-01), Hubner et al.
patent: 4012374 (1977-03-01), Wade et al.
patent: 4024151 (1977-05-01), Wade et al.
patent: 4213989 (1980-07-01), Nedelec et al.

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