Substituted 2-amino-4(1H)pyridones, 7-pyrrolo[1,2-a]pyridinones,

Details Substituted 2-amino-4(1H)pyridones, 7-pyrrolo[1,2-a]pyridinones, Substituted 2-amino-4(1H)pyridones, 7-pyrrolo[1,2-a]pyridinones,

1984-02-08

1986-07-22

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514226, 514299, 514301, 514306, 514352, 514353, 546297, 546138, 546114, 546183, 544 47, 2602444, A61K 3155, C07D22104

Patent

active

046020136

ABSTRACT:
Substituted 2-amino-4(1H)pyridones are provided which are renal vasodilators and bronchodilators.

REFERENCES:
patent: 3334091 (1967-08-01), Houlihan
patent: 4288438 (1981-09-01), Kubo et al.
Kappe et al., Monatsh. Chem., 1983, 114(8-9), pp. 953-963, Abstracted by Chem. Abstracts vol. 100: 51410z, (1984).
"A Guide to the Chemical Basis of Drug Design", by Alfred Burger, John Wiley & Sons, New York, pp. 134-138, (1983), Section 3.11-3.11.1.
Drugs of the Future, "Biologically Active 1,4-Dihydropyridine Derivatives", vol. VI, No. 7, 1981, J. Prous et al.
Vinick et al., Tetrehedron Letters, N044, pp. 4221-4224, (1978), discloses several 4(1H)-pyridones.

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