Cyclic adhesion inhibitors

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Cyclic peptides

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Details

530330, 530338, 514 9, 514 11, C07K 700

Patent

active

060019611

ABSTRACT:
The invention relates to novel cyclopeptides of the formula I

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patent: 4792525 (1988-12-01), Ruoslahti et al.
patent: 5849692 (1998-12-01), Jonczyk et al.
Aumailley et al., "Strong and selective inhibitors of cell adhesion . . . ", FEBS Letters, vol. 291, No. 1, Oct. 1991, pp. 50-54.
Jackson et al., J. Am. Chem. Soc., 116(8), pp. 3220-3230, 1994.
Coy et al., Tetrahedron, 44(3), 835-41, 1988.

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