Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1996-10-07
1999-01-05
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544295, 544296, 544238, 544122, 544123, 544 82, C07D23947, C07D40312, C07D40314
Patent
active
058564845
ABSTRACT:
Compounds of formula I: ##STR1## are disclosed. The compounds inhibit the binding of endothelin to its receptors.
REFERENCES:
patent: 5270313 (1993-12-01), Burri et al.
patent: 5292740 (1994-03-01), Burri et al.
patent: 5420129 (1995-05-01), Breu et al.
patent: 5541186 (1996-07-01), Breu et al.
Abstract Accession Number 97-214767/20 Incomplete Citation.
Life Sci, 44:1429 (1989).
Adachi et al., BBRC 180:1265-1272.
Breu Volker
Burri Kaspar
Cassal Jean-Marie
Clozel Martine
Hirth Georges
Ford John M.
Hoffmann-La Roche Inc.
Johnston George W.
Pokras Bruce A.
Tramaloni Dennis P.
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