Surgery – Truss – Pad
Patent
1982-12-15
1985-05-28
Cohen, Lee S.
Surgery
Truss
Pad
128905, 128700, A61B 502
Patent
active
045193959
ABSTRACT:
A medical instrument includes a noninvasive pulse transducer which senses heart beats of a human subject. Based upon pulse signals from the transducer, the instrument provides visual stimulae which allow the human subject to voluntarily synchronize the subject's respiration cycles with the subject's heart beats. At the same time, the instrument determines and stores the instantaneous beat-to-beat heart rate for each beat of the respiratory cycles. After a predetermined number of synchronized respiratory cycles have been completed, the instrument performs both classical statistical and rhythmometric analyses utilizing the stored instantaneous heart rates. The instrument determines from these analyses mean and standard error values for each beat of the respiratory cycle; an analysis of variance of the mean value; a rhythm qualified mean heart rate value; an amplitude value; a timing value (which indicates the location of the peak of the cosine curve best fitting the heart rate data within the respiratory cycle), and a percent rhythm value (which indicates the quality of the fit with the cosine curve to the stored instantaneous heart rates). The amplitude value provides an indication of the physiological (as opposed to chronological) cardiovascular age of the human subject, since it indicates the compliance of the heart tissue. The effect of cardiotoxins, cardiac drugs, other substances, as well as altered physiologic states upon a subject's heart tissue compliance also can be monitored using the amplitude, mean and peak timing values produced by the instrument. The instrument provides a displayed and/or printed output so that the subject or his or her physician has a simple yet accurate indication of heart condition which may be evaluated periodically and followed over time.
REFERENCES:
patent: 3661147 (1972-05-01), Mason et al.
patent: 4281663 (1981-08-01), Pringle
patent: 4338950 (1982-07-01), Barlow, Jr. et al.
patent: 4355644 (1982-10-01), Saito
Akselrod, S., et al., "Power Spectrum Analysis of Heart Rate Fluctuation: a Quantitative Probe of Beat-to-Beat Cardiovascular Control", Science 213:220-222, 1981.
Williams, A., Gropper, A., "Interrelationships of Cardiac Output, Blood Pressure, and Peripheral Resistance During Normal Respiration in Normotensive and Hypertensive Individuals", Circulation 4:278-286, 1951.
Chess, G., Tam, R., Calaresco, F., "Influence of Cardiac Neural Inputs on Rhythmic Variations of Heart Period in the Cat", Am. J. of Physiology 228:775-781, 1975.
Womak, B., "The Analysis of Respiratory Sinus Arrhythmia Using _Special Analysis and Digital Filtering", IEEE Transactions on Biomedical Engineering 18:399-409, 1971.
Flaherty, J., "Influence of Respiration on Recording Cardiac Potentials", Am. J. of Cardiology 20:21-28, 1967.
Fischmann, E., et al., "Beat to Beat and Observer Variation of the Electrocardiogram", American Heart Journal 75:465-473, 1968.
Lauson, H., et al., "The Influence of the Respiration on the Circulation in Man", Am. J. of Medicine 1:315-336, 1946.
Starr, I., et al., "On the Cause of the Respiratory Variation of the Ballistocardiogram, with a Note on Sinus Arrhythmia", J. of Clin. Investiation 25:53-64, 1946.
Bainbridge, F. A., "The Relationship Between Respiration and the Pulse Rate", J. Physiol. 54:192-202, 1920.
Almasi, J., Schmitt, O., "Basic Technology of Voluntary Cardiorespiratory Synchronization in Electrocardiology", IEEE Transactions on Biomedical Engineering 21:264-273, 1974.
Sokal, R. et al., Biometry, The Principles and Practice of Statistics in Biological Research, Chapters 4 and 8, (1969).
Cornelissen, G., et al., "Chronobiometry with Pocket Calculators and Computer Systems", La Ricerca Clin. Lab., 10, 333, (1980).
Halberg, F., "Auto-rhythmometry Procedures for Physiologic Self-measurements and Their Analysis", Phsiol. Teach. 1:1-11, (1972).
Hotelling, H., Annals of Mathematical Statistics, vol. 2, p. 360, (1931).
Cohen Lee S.
Sykes Angela D.
LandOfFree
Medical instrument for noninvasive measurement of cardiovascular does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Medical instrument for noninvasive measurement of cardiovascular, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Medical instrument for noninvasive measurement of cardiovascular will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-863616