Use of xanthine derivatives for the inhibition of dephosphorylat

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514264, 514907, A61K 3152

Patent

active

058563300

ABSTRACT:
Compounds of the formula I ##STR1## where one of the radicals R.sup.1 and R.sup.3 is a radical of the formula II --(CH.sub.2).sub.n --A--CH.sub.3 (II) in which A is a covalent bond, --C(O)-- or --C(R.sup.4)(OH)--, are suitable for the production of pharmaceuticals for the modulation of apoptosis. A combination preparation comprising a compound of the formula I and a compound of the formula IV and/or V ##STR2## is suitable for the production of pharmaceuticals for the modulation of apoptosis.

REFERENCES:
patent: 3737433 (1973-06-01), Mohler et al.
patent: 4061767 (1977-12-01), Ertel et al.
patent: 4108995 (1978-08-01), Mohler et al.
patent: 4833146 (1989-05-01), Gebert et al.
patent: 5240960 (1993-08-01), Hambleton et al.
patent: 5308865 (1994-05-01), Bartlett et al.
R. Turner, "Use of xanthine derivs. esp. . . . pentoxifyllilne . . . for inhibiting interleuken-8 elaboration and treating a symptom of an upper respiratory viral infection, esp. a rhinovirus infection", Derwent abstract No. 96-151131 for WO 96/05836, (1996).
P. Dugel et al., "Treatment of AIDS-associated optic neuropathy-by oral admin. of . . . pentoxifylline . . . and other tumour necrosis factor blockers", Derwent abstract No. 93-320439 for WO 93/18770, (1993).
J. Bianco et al., "Modulation of cellular response using substd. xanthine (s) -- for prevention of bone marrrow rejection and treatment of tumours, leukaemia, bacterial, viral, fungal or protozoal infection, etc.", Derwent abstract No. 92-433353 for WO 92/21344, (1992).
D. Steiffge et al., "Use of . . . pentoxifylline . . . in medicaments-for treating inflammatory disorders", Derwent abstract No. 90-024285 for EP 0 351 885, (1990).
CA 123:160563, Mentz et al. 1995.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of xanthine derivatives for the inhibition of dephosphorylat does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of xanthine derivatives for the inhibition of dephosphorylat, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of xanthine derivatives for the inhibition of dephosphorylat will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-862553

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.