2-Naphthyl acetic acid derivatives and compositions and methods

Details 2-Naphthyl acetic acid derivatives and compositions and methods 2-Naphthyl acetic acid derivatives and compositions and methods

1978-03-27

1980-06-10

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603458R, 560 10, 560 56, 562427, 562466, C07D30906, C07C 63595, C07C 6976

Patent

active

042072417

ABSTRACT:
2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, antipyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.

REFERENCES:
patent: 3562336 (1971-02-01), Nelson
patent: 3792167 (1974-02-01), Fried et al.

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