Regulators of UCP2 gene expression

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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435243, 4353201, 435410, 536 231, 536 241, C12N 510, C12N 100, C12N 1511, C12N 1563

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active

058077405

ABSTRACT:
The invention relates to regulators of UCP2 gene transcription, including novel UCP2 transcriptional promoters. UCP2 gene promoters are used in diagnosis and pharmaceutical development. In particular, transfected cells comprising UCP2 gene promoters operably linked to a reporter are used in high-throughput pharmaceutical screens.

REFERENCES:
Fleury et al, Nature Genetics, vol. 15(3), pp. 269-272, Mar. 1997.

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