Human stem cell antigens

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4352523, 4353201, 435325, 536 235, C12N 1512, C12N 1570, C12N 1574, C12N 1585

Patent

active

058561366

ABSTRACT:
The present invention provides polynucleotides encoding stem cell antigens, the partial sequences for which were initially isolated from THP-1 and bladder tumor cDNA libraries and which identify and encode novel human stem cell antigens. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding the stem cell antigens.

REFERENCES:
patent: 5468612 (1995-11-01), Cohen et al.
Mao, M. et al., "RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell", Proc. Natl. Acad. Sci. USA, 93: 5910-5914 (1996).
Triglia T, et al. "A procedure for in vitro amplification of DNA segments that lie outside the boundaries of known sequences." Nucl. Acids Res. 16: 8186-8187, 1988.
Fleming et al., "Characterization of Two Novel Ly-6 Genes", (1993), J Immunol, vol. 150(12), pp. 5379-5390.
Blake et al., "Ly-6 Is Kidney s Widely Expressed on Tubular Epithelium and Vascular Endothelium and is Upregulated by Interferon Gamma", (1993), J Am Soc Nephrol, vol. 4(5), pp. 1140-1150.
Godfrey et al., "Thymic shared antigen-1. A Novel Thymocyte Marker Discriminating Immature from Mature Thymocyte Subsets", (1992), J Immunol, vol. 148, pp. 2006-2011.
MacNeil et at., "Isolation of a cDNA Encloding Thymic Shared Antigen-1", J Immunol, vol. 151, pp. 6913-6923.
Fleming et al., "Multiple Glycosylphosphatidylinositol-Anchored Ly-6 Molecules and Transmembrane Ly-6E Mediate Inhibition of IL-2 Production", (1994), The Journal of Immunology, vol. 153, pp. 1955-1962.
Classon et al., "Mouse stem cell antigen Sca-2 is a member of the Ly-6 of cell surface proteins", (1994), Proc. Natl. Acad. Sci., vol. 91, pp. 5296-5300.
Lin et al., "Characterization of A1, a Novel Hemopietic-Specific Early-Response Gene with Sequence Similarity to bcl-2", (1993), The Journal of Immunology, vol. 151, pp. 1979-1988.
Katz et al., "An Association Between High Ly-6A/E Expression on Tumor Cells and a Highly Malignant Phenotype", (1994), Int. J. Cancer, vol. 59, pp. 684-691.
Terstappen et al., "Assessment of Hematopoietic Cell Differentiation by Multidimensional Flow Cytometry", (1993), Journal of Hematotherapy, vol. 2, pp. 431-447.
Classon, B.J. and Coverdale, L., (Direct Submission) (1996)), GenBank Sequence Database, National Center for Biotechnology Information, National Library of Medicine, Building 38A, Room 8N805, Bethesda, MD 20894.
Constanzi, C. And Pehrson, J.R. (GI 1711126), GenBank Sequence Database (Accession U79139), National Center for Biotechnology Information, National Library of Medicine, Methesda, Maryland 20894.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Human stem cell antigens does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human stem cell antigens, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human stem cell antigens will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-861279

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.