Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-10-30
1999-01-05
Teng, Sally P.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4352541, 4353201, 435325, 536 235, 536 2431, C12N 1512, C07K 14705
Patent
active
058561293
ABSTRACT:
The present invention provides a novel human P.sub.2X purinoreceptor (HPURR) and polynucleotides which identify and encode HPURR. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPURR and a method for producing HPURR. The invention also provides for use of HPURR, and agonists, antibodies or antagonists specifically binding HPURR, in the prevention and treatment of diseases associated with expression of HPURR. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPURR for the treatment of diseases associated with the expression of HPURR. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HPURR.
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Coleman Roger
Hillman Jennifer L.
Billings Lucy J.
Incyte Pharmaceuticals Inc.
Teng Sally P.
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