Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1997-03-24
1999-01-05
Azpuru, Carlos A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424443, 424445, 424449, A61F 1302, A61L 1516
Patent
active
058559078
ABSTRACT:
The present invention relates to, among other things, methods of treatment of migraine headache in humans with reduced side effects by the topical administration of a migraine-ameliorating effective amount of an opioid, singly, or in combination with other pharmacological agents, including vasoconstrictors, antiinflammatory agents, antimicrobial agents, decongestants and non-opioid migraine drugs.
REFERENCES:
patent: 5565568 (1996-10-01), Cho et al.
Marr, et al., Am. J. of Opthalmology, vol. 43, pp. 606-610, (1957).
Edvinsson, et al., "Adrenergic, cholinergic and peptidergic nerve fibres in dura matter--involvement in headache?" Cephalagia, vol. 1, pp. 175-179, (1981).
Barre, "Cocaine as an Abortive Agent in Cluster Headache," Journal of Headache, vol. 22, pp. 69-73, (1982).
Awouters, et al., "Pharmacology of Antidiarrheal Drugs" Ann. Rev. Pharmacol Toxicol vol. 23, pp. 279-301, (1983).
Hiner, et al., "Antimigraine Drug Interactions with 5-Hydroxytrytamine.sub.1A Receptors" Annals of Neurology, vol. 19, pp. 511-513, (1986).
Waeber, et al., "GR 43175: A Preferential 5-HT.sub.1D Agent in Monkey and Human Brains as Shown by Autoradiography" Synapse, vol. 4, pp. 168-170, (1989).
Dihn, et al., "Cerebral Vasodilation after the Thermocoagulation of the Trigeminal Gaglion in Humans" Neurosurgery, vol. 31, No. 4, pp. 658-663, (1992).
Davidoff, "Migraine: Manifestation, Pathogenesis and Management" Published by F.A. Davis Company of Philadelphia, U.S.A., pp. 242 (1995).
Kudrow, et al., "Rapid and Sustained Relief of Migraine Attacks with Intranasal Lidocaine: Preliminary Findings," Headache, vol. 25, pp. 79-82, (1995).
Maizels, et al., "Intranasal Lidocaine for Treatment of Migraine" JAMA, vol. 276, pp. 319-321, (1996).
Diamond, et al., "Long-term Study of Proranolo in the Treatment of Migraine." Headache, vol. 22, pp. 268-271, (Sep. 1982).
Engelstoft, et al., "Synthesis and 5HT Modulating Activity of Stereoisomers of 3-Phenoxymethyl-4-phenylpiperidines." Acta Chemica Scandanavica vol. 50, pp. 164-169, (1996).
Fischer, et al., "Butorphanol (Stadol): A Study in problems of current drug information and control.", OJAAN, vol. 48, No. 5, May 1997.
Kudrow, Lee, "Natural History of Cluster headaches --Part 1 Outcome of Drop-out Patients." Headache, vol. 22, (Sep. 1982).
Peregaard, et al., ".sigma. Ligands with Subnanomars Affinity and Preference for the .sigma..sub.2 Binding Site. 1,3-(.omega.-Aminoalkyl) -1H-indoles." J. Med. Chem. vol. 38, pp. 1998-2008, (1995).
Shaw, et al., "Effects of Phenylpiperidine Opioids Antagonists on Food Consumption and Weight Gain of the Obese Zucker Rat." , J. of Pharm. and Experimental Therapeutics, vol. 253, No. 1, Dec. 18, 1989.
Soneson, et al., "Substituted (S)-Phenylpiperidines and Rigid Congeners as Preferential Dopamines Autoreceptor Antagonists: Synthesis and Structure-Activity Relationships." J. Amer. Chem., vol. 37, pp. 2735-2753, (1994).
Sonesson, et al., "Substituted 3-Phenylpiperidines: New Centrally Acting Dopamines Autoreceptor Antagonists." J. Amer. Chem., vol. 36, pp. 3188-3196, (1993).
Fisher et al., Butorphanol (stadol): A study in problems of current drug information and control, Neurology (1997), 48(5), 1156-1160.
LandOfFree
Method of treatment of migraine does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of treatment of migraine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of treatment of migraine will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-859852