Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic polymer or copolymer
Patent
1995-06-07
1999-01-05
Woodward, Michael P.
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Synthetic polymer or copolymer
536 111, 424 111, 4242091, 514 75, 514110, 514114, 514137, A61K 3939, A61K 4500, A61K 4505
Patent
active
058558950
ABSTRACT:
A polyphosphazene polyelectrolyte immunoadjuvant having improved water solubility, a vaccine composition of the immunoadjuvant and an antigen or immunogen and methods of their use in producing or enhancing an immunoprotective response in a host are disclosed.
REFERENCES:
patent: 5284934 (1994-02-01), Allen
patent: 5494673 (1996-02-01), Andrianov et al.
Cohen et al., "Ionically Cross-Linkable Polyphosphazene: A Novel Polymer for Microencapsulation ", J. Amer. Chem. Soc. 112,7832-7833.
Andrianov et al., "Controlled release using ionotropic polyphosphazene hydrogels"J. Contr. Rel. 27, 69-77.
Aldrich Chemical Catalog, p. 731.
Andrianov Alexander K.
Payne Lendon G.
Sargent Jonathan R.
Sule Sameer S.
Lee Datquan
Olstein Elliot M.
Semionow Raina
Virus Research Institute
Woodward Michael P.
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