Monoclonal antibodies and methods for fungal pathogen detection

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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43524027, 435948, 435 7, 435188, 424 11, 424 858, 436518, 935100, 935104, C12N 500, C07K 1504, A61K 39395

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048451975

ABSTRACT:
This invention provides monoclonal antibodies useful for the detection of Phythiaceae infection of plants. Hybridoma producing the antibodies as well as materials and kits for carrying out the detection of the organisms are also disclosed.

REFERENCES:
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patent: 4404279 (1983-09-01), Ricotti et al.
patent: 4427653 (1984-01-01), Springer
Savage, S. D. et al., Phytopathology, 71 (4): 411-415 (1981), cited in Biosis abstract 81: 255952.
Adams, G. C. Jr. et al., Phytopathology, 69(6): 629-633 (1979), cited in Biosis abstract 80: 150935.
Can. J. Botany 58:1412-16 (1980) J. Krywienczyk & C. E. Dorworth, "Seriological Relationships of Some Fungi of the Genus Pythium".
Nature 256:495-97 (1975) G. Kohler and C. Milstein, "Continuous Cultures of Fused Cells Secreting Antibody of Predefined Specificity".
Science 145:709 (1964) J. W. Littlefield, "Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants".
ASM News 50(3):99-102 (1984) H. T. Hsu et al., "Monoclonal Antibodies and Plant Viruses".
Eur. J. Immunol. 7:743-746 (1977) G. J. Hammerling, "T-Lymphocyte Tissue Culture Lines Produced by Cell Hybridization".

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