N-[4-o-hydroxyphenyl-1,3-dioxan-5-ylhexenoyl]sulphonamides

Details N-[4-o-hydroxyphenyl-1,3-dioxan-5-ylhexenoyl]sulphonamides N-[4-o-hydroxyphenyl-1,3-dioxan-5-ylhexenoyl]sulphonamides

1987-04-20

1989-07-04

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549373, A61K 31335, C07D31906

Patent

active

048451207

ABSTRACT:
The invention concerns novel N-[4(Z)-2-substituted-6-(4-o-hydroxyphenyl-1,3 dioxan-cis-5-yl)hexenoyl]sulphonamide derivatives of formula I of value as therapeutic agents. Typically R.sup.1 is a branched (3-6C)alkyl, trifluoromethyl or phenyl radical as defined hereinafter and R.sup.2 is alkyl, benzyl or phenyl.
The invention also discloses salts of the formula I compounds as well as pharmaceutical compositions containing the compounds and processes for the production of the compounds.

REFERENCES:
patent: 4567197 (1986-01-01), Brewster et al.

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