Peptide aldehydes as antithrombotic agents

Details Peptide aldehydes as antithrombotic agents Peptide aldehydes as antithrombotic agents

1994-04-11

1995-01-10

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 546153, 546348, 548146, 548492, 548535, 562 70, 562445, 562556, 562575, A61K 3700, A61K 3702, C07K 906, C07K 508

Patent

active

053807138

ABSTRACT:
This invention relates to novel arginine aldehydes, their salts and hydrates, which compounds selectively exhibit serine proteases inhibitory activity, are highly stable in aqueous solutions, and are useful for anti-trypsin and anti-thrombin activity.

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Bajusz, et al., J. Med. Chem., 33: 1729-35, (1990).

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