Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1997-12-31
1999-08-03
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
564346, 564338, 564300, 564285, A61K 31135, C07C21710
Patent
active
059326204
ABSTRACT:
salt: ##STR1## has a NGF activity-potentiating effect and is useful as a remedy for various diseases caused by degeneration of central nervous system or peripheral nervous system such as senile dementia of Alzheimer type, Huntington's chorea, various neuropathies, Riley-Day syndrome, traumatic nerve injury, amyotrophic lateral sclerosis (ALS) and the like.
REFERENCES:
patent: 5280032 (1994-01-01), Ono et al.
patent: 5472984 (1995-12-01), Ono et al.
patent: 5612381 (1997-03-01), Ono et al.
patent: 5658904 (1997-08-01), Ono et al.
patent: 5719150 (1998-02-01), Ono et al.
Chemical Abstracts, vol. 119, No. 9, p. 72; col. 2; XP002048283; Aug. 30, 1993 S. Ono, et al.: "Protective effect of R(-)-1- hydrochloride (T-588), a novel cerebral activator, against experimental cerebral anoxia."
Hirata Kazunari
Maekawa Mutsuko
Narita Hirokazu
Ono Satoshi
Aulakh Charanjit S.
Rotman Alan L.
Toyama Chemical Co., Ltd.
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