Biotextured surfaces

Stock material or miscellaneous articles – Hollow or container type article – Polymer or resin containing

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428 357, 428 39, 428103, B29D 2322, B32B 108

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active

053805895

ABSTRACT:
Synthetic biotextured surfaces and methods to produce the surface are disclosed. The surfaces mimic the topography of a surface of a naturally occurring sub-endothelial or sub-epithelial extracellular matrix. This is achieved by removing a cell layer from the naturally occurring extracellular matrix substrate, covering the extracellular matrix with a casting material, and allowing the casting material to harden. One then removes extracellular matrix from the casting material to uncover a negative core, and then uses the negative core to cast the replica material. By removing the negative core from the replica material one then creates the synthetic surface.

REFERENCES:
D. Steeber, et al., 1 Scanning Microscopy 831-839 (1987).
K. Hodde, et al., 4 Scanning Microscopy 693-704 (1990).
D. Steeber, et al., 313-329 in Scanning Electron Microscopy Of Vascular Casts (1992).
D. Bjorling, et al., 28 J. Pham. Tox. Meth. 149-157 (1992).
R. Whalen, 34 Trans. Am. Soc. Artif. Intern. Organs 887-892 (1988).
S. Williams, et al., 4 Scanning Microscopy 181-189 (1990).
J. Schmidt, et al., 12 Biomaterials 385-390 (1991).
D. Stenger, et al., 114 J. Am. Chem. Soc. 8435-8442 (1992).
I. Amato, 258 Science 1084 (1992).
B. Brune, USA Today (Mar. 1, 1993).
F. Lefebvre, et al., 13 Biomater. 28-33 (1992).
L. Bordenave, et al., 13 Biomater. 439-446 (1992).
S. Taylor, et al., 17 J. Biomed. Mat. Res. 205-227 (1983).
C. Weinberg, et al., 231 Science 397-400 (1986).
E. Einarsson, et al., Scanning Electron Microscopy I 273-278 (1984).
D. Ingbar, et al., 109 J. Cell. Biol. 317-330 (1989).
S. Goodman, et al., in Colloidal Gold; Principles, Methods, And Applications, vol. 3, 369-409 (1991).
S. Williams, et al., 26 J. Biomed. Mat. Res. 103-117 (1992).

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