Bicyclic nucleosides, oligonucleotides, process for their prepar

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 283, 536 284, 536 285, 536 2851, 536 2852, 536 2853, 536 2854, 536 2855, 544298, 544309, 544314, 544317, C07H 1906, C07D23902, C07D23906, C07D23922

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active

053938780

ABSTRACT:
Compounds of the formula I in the form of the racemates or enantiomers thereof, ##STR1## in which R.sub.1 and R.sub.2 independently of one another are hydrogen or a protective group, and B is a purine or pyrimidine radical or an analogue thereof, can be used as antiviral active ingredients or for the preparation of biologically active oligonucleotides.

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E. Uhlmann et al. Chem. Reviews vol. 90, No. 4 (1990) 543-584.
V. Marquez et al. Medicinal Research vol. 6 No. 1 (1986) 1-40.
Fissekis et al. "Synthesis of 5-Hydroxyalkyl-pyrimedines from Lactones III, 5-Dihydroxycyclee-pentyl Pyrimidines" (1967) pp. 395-3603.

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