Human nucleolin-like protein

Details Human nucleolin-like protein Human nucleolin-like protein

1997-12-12

1999-08-03

Huff, Sheela

Chemistry: molecular biology and microbiology

Vector, per se

530350, 536 231, 536 235, 435 691, 435 6, C12N 1500

Patent

active

059324759

ABSTRACT:
The invention provides a human nucleolin-like protein (HNLP) and polynucleotides which identify and encode HNLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HNLP.

REFERENCES:
Lapeyre, B. et al., "Nucleolin, the major nucleolar protein of growing eukaryotic cells: An unusual protein structure revealed by the nucleotide sequence", Proc. Natl. Acad. Sci. USA, 84: 1472-1476 (1987).
Erard, M.S. et al., "A major nucleolar protein, nucleolin, induces chromatin decondensation by binding to histone H1", Eur. J. Biochem., 175: 525-530 (1988).
Deng, J.S. et al., "Internalization of anti-nucleolin antibody into viable HEp-2 cells", Mol. Biol. Rep., 23: 191-195 (1996).
Bell, S.A. et al., "Specificity of antinuclear antibodies in scleroderma-like chronic graft-versus-host disease: clinical correlation and histocompatibility locus antigen association", Br. J. Dermatol., 134: 848-854 (1996).
Zaidi, S.H.E. and J.S. Malter, "Nucleolin and Heterogeneous Nuclear Ribonucleoprotein C Proteins Specifically Interact with the 3'-Untranslated Region of Amyloid Protein Precursor mRNA", J. Biol. Chem., 270: 17292-17298 (1995).
Lapeyre, B. et al., (Direct Submission), GenBank Sequence Database (Accession 128842), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 128842).

Affiliated with

Also associated with

Rating

Human nucleolin-like protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human nucleolin-like protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human nucleolin-like protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-849010