Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Patent
1997-10-15
1999-08-03
Hendricks, Keith D.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
435194, 43525233, 4353201, 4351721, 536 232, C12N 1509, C12N 1554, C12N 1563
Patent
active
059324538
ABSTRACT:
A DNA encoding aspartokinase III derived from bacteria of the genus Escherichia and having mutation by which feedback inhibition with L-lysine is released is introduced into cells to form transformant bacteria of the genus Escherichia. These bacteria are incubated in an appropriate culture medium. An L-amino acid is produced and accumulated in the culture, and collected from this culture.
REFERENCES:
patent: 5243039 (1993-09-01), Schendel et al.
patent: 5367110 (1994-11-01), Galili et al.
patent: 5661012 (1997-08-01), Sano et al.
Cassan et al. Nucleotide sequence of lysC gene encoding the lysine-sensitive aspartokinase III of Escherichia coli K12. J. Biol. Chem. 261(3) : 1052-1057 (1986).
Kikuchi Yoshimi
Kojima Hiroyuki
Nakanishi Kazuo
Ajinomoto Co. Ltd.
Hendricks Keith D.
Mayhew Bradley S.
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