Process for producing L-amino acid through fermentation

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435194, 43525233, 4353201, 4351721, 536 232, C12N 1509, C12N 1554, C12N 1563

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active

059324538

ABSTRACT:
A DNA encoding aspartokinase III derived from bacteria of the genus Escherichia and having mutation by which feedback inhibition with L-lysine is released is introduced into cells to form transformant bacteria of the genus Escherichia. These bacteria are incubated in an appropriate culture medium. An L-amino acid is produced and accumulated in the culture, and collected from this culture.

REFERENCES:
patent: 5243039 (1993-09-01), Schendel et al.
patent: 5367110 (1994-11-01), Galili et al.
patent: 5661012 (1997-08-01), Sano et al.
Cassan et al. Nucleotide sequence of lysC gene encoding the lysine-sensitive aspartokinase III of Escherichia coli K12. J. Biol. Chem. 261(3) : 1052-1057 (1986).

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