Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Hormone or other secreted growth regulatory factor,...
Patent
1996-07-18
1998-09-15
Scheiner, Toni R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Hormone or other secreted growth regulatory factor,...
514 56, 530399, 536 21, 607 3, 607 50, A61K 3818, C07K 1450, A61N 118
Patent
active
058075569
ABSTRACT:
Methods of reducing the degeneration of a tissue resulting from mobilization with or without chronic, continuous electrical stimulation by administering basic fibroblast growth factor or heparin to the tissue are provided.
REFERENCES:
Baffour et al., "Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: Dose-response effect of basic fibroblast growth factor," J. Vasc. Surg. 1992, 16:181-191.
Bailey et al., "Chronic Stimulation Enhances Extramyocardial Collateral Bloof Flow After a Cardiomyoplasty", Ann. Thorac. Surg. 1993 56:1045-1053.
Banai et al., "Angiogenic-Induced Enhancement of Collateral Bloof Flow to Ischemic Myocardium by Vascular Endothelial Growth Factor in Dogs", Circulation 1994, 89:2183-2189.
Battler et al., "Intracoronary Injection of Basic Fibroblast Growth Factor Enhances Angiogenesis in Infarcted Swince Myocardium", JACC 1993, 22:2001-2006.
Blood et al. "Basic Fibroblast Growth Factor Identified in Chronically Stimulated Cardiomyoplasties", Ann. Thorac. Surg. 1994, 58:1320-1326.
Casscells et al., "Isolation, Characterization and Localization of Heparin-binding Growth Factors in the Heart", J. Clin. Invest. 1990, 85:433-441.
Durham et al., "Regional Perfusion of Latissimus Dorsi Pedicle Flaps in Dynamic Cardiomyopolasty", JACC 1992, 19:353A.
Eldelman et al., "Perivascular and intravenour administration of basic fibroblast growth factor: Vascular and solid organ deposition", Proc. Nat'l Acad. Sci. 1993, 90:1513-1517.
Folkman J. and Klagsbrun M., "Angiogenic Factors" Science 1987, 235:442-447.
Galloway et al., "Do ischemic hearts stimulate endothelial cell growth?", Surgery 1984, 96:435-439.
Gospodarowicz et al., "Structural Characterization and Biological Functions of Fibroblast Growth Factor", Endocrine Review 1987, 8:95-114.
Kalil-Filho et al., "Magnetic Resonance Imaging Evaluation of Chronic Changes in Latissimus Dorsi Cardiomyoplasty", Circulation 1994, 90:II-102--II-106.
Kratz et al., "The relation between latissimus dorsi skeletal muscle strucure and contractile function after cardiomyoplasty", J. Thorac. Cardiovasc. Surg. 1994, 107:868-878.
Levin et al., "Alterations in Regional Mechanics and Blood Flow Can Explain Lack of Benefit During Cardiomyoplasty", Circulation 1991, 94:II-355.
Lucas et al., "Long-Term Follow-Up (12 to 35 Weeks) After Dynamic Cardiomyoplasty", JACC 1993, 22:758-767.
Magovern et al., "Operation for Congestive Heart Failure: Transplantation, Coronary Artery Bypass, and Carciomyoplasty", Ann. Thorac. Surg. 1993, 56:418-25.
Magovern et al., "Paced Skeletal Muscle for Dynamic Cardiomyoplasty", Ann. Thorac. Surg. 1988, 45:614-619.
Mannion et al., "Techiques to Enhance Extramyocardial Collateral Blood Flow After a Cardiomyoplasty", Annals of Surgery 1993 218:544-554.
Mannion et al., "Acute Electrical Stimulation Increases Extramyocardial Collateral Blood Flow After a Cardiomyoplasty", Ann. Thorac. Surg. 1993 56:1351-1358.
Moreira et al., "Current Expectations in Dynamic Cardiomyoplasty", Ann. Thorac. Surg. 1993, 55:299-303.
Morrow et al., "Increased Expression of Fibroblast Growth Factors in a Rabbit Skeletal Muscle Model of Exercise Conditioning", J. Clinical investigation 1990, 85:1816-1820.
Pu et al. "Enhanced Revascularization of the Ischemic Limb by Angiogenic Therapy", Circulation 1993, 88:208-215.
Radermecker et al., "Influence of Tension Reduction and Peripheral Dissection on Histologic, Biochemical and Bioenergetic Profiles, and Kinetics of Skeletal Muscle Fast-to-Slow Transformation", J. Card. Surg. 1991, 6:Supp. 195-203.
Spirito et al., "Immunohistochemical Localization of Basic and Acidic Fibroblast Growth Factors in the Developing Rat Heart", Circulation 1991, 84:322-332.
Takeshita et al., "Therapeutic Angiogenesis", J. Clin. Invest. 1994, 93:662-670.
Unger et al., "Basic fibroblast growth factor enhances myocardial collateral flow in a canine model", Am J. Physiol. 1994, 266:H1588-H1595.
Yanagiasawa-Miwa et al., "Salvage of Infarcted Myocardium by Angiogenic Action of Basic Fibroblast Growth Factor", Science 1992, 257:1401-1403.
DeFeudis, F.V. 1991, Life Science, 49: 689-705.
Harada, K. et al. 1994, J. Clin. Invest. 94:623-630.
Mannion, et al., "Effects of Collateral Blood Vessel Ligation and Electrical Conditioning on Blood Flow in Dog Latissimus Dorsi Muscle", J. Surg. Res, 47:322-340, 1989.
Magno Michael G.
Mannion John D.
Johnson Nancy A.
Scheiner Toni R.
Thomas Jefferson University
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