Method of preparing (S)-1-phenyl-1,3-propanediol or derivatives

Details Method of preparing (S)-1-phenyl-1,3-propanediol or derivatives Method of preparing (S)-1-phenyl-1,3-propanediol or derivatives

1992-11-16

1995-02-28

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435280, C12P 722

Patent

active

053936647

ABSTRACT:
(S)-1phenyl-1,3-propanediol or a derivative thereof having high optical purity can be produced simply in high yield, by contacting 1-phenylpropan-3-ol-1-one with a culture of microorganisms, microorganism cells isolated from the culture, or a product obtained by processing the microorganism cells.

REFERENCES:
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Christen M. et al, J. Chem. Soc., Chem Commun pp. 264-266 (1988).
Hummel W., Appl Micro Biol Biotechnol 34:15-19 (1990).
Jones, J. B., Tetrahedron 42:3351-3403 (1986).
Hudlicky T. et al, J. Org. Chem 55: 4767-70 (1990).
Chemical Abstracts, vol. 119, No. 25, Dec. 20, 1993, p. 825, AN-269201w.

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