Dideoxynucleoside-5'-phosphonoformic acid compounds

Details Dideoxynucleoside-5'-phosphonoformic acid compounds Dideoxynucleoside-5'-phosphonoformic acid compounds

1990-05-10

1992-07-21

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 28, 536 29, C07H 1900

Patent

active

051324148

ABSTRACT:
Compounds having the structure ##STR1## in which R is alkyl, aryl, or aralkyl, A is hydrogen or a water-soluble cation, B is hydrogen, fluorine, or azido, the bond is saturated when B is fluorine or azido and is saturated or unsaturated when B is hydrogen, and D is a purine or pyrimidine base are effective inhibitors of retrovirus replication.

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