Method and product for increasing fertility in sheep using milk

Details Method and product for increasing fertility in sheep using milk Method and product for increasing fertility in sheep using milk

1986-10-24

1988-06-07

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 85, 530406, 530410, 530832, 2603975, A61K 39385, C07K 17016

Patent

active

047495677

ABSTRACT:
A product and method for increasing fertility in sheep. By "increasing felity" is meant increasing the potential of a flock of sheep to multiply by increasing ovulation in ewes. The product is an immunogenic conjugate of 4-androstene-3, 17-dione and a soluble milk protein (SMP): 6-hydroxyandrost-4-ene-3, 17-dione 6-hemisuccinyl: SMP. The method comprises immunizing the ewes in a flock of sheep against 4-androstene-3, 17-dione by administering 6-hydroxyandrost-4-ene-3, 17-dione 6-hemisuccinyl SMP at the rate of 3 to 5 mg per ewe. In previously untreated ewes, two administrations are required at between 8 to 9 and 4 to 5 weeks before the planned commencement of mating. Subsequent administrations are annually and are recommended at 5 weeks before the commencement of mating.

REFERENCES:
patent: 4150105 (1979-04-01), Gross
patent: 4197286 (1980-04-01), Rao
patent: 4331657 (1982-12-01), Cox et al.
patent: 4457914 (1984-07-01), Cox et al.
J. Endocrinol. 81 (1979), 249-259, Martenz et al.
Aust. J. Exp. Agric. Anim. Husb. 19 (1979), 673-678, Martin et al.
Proc. Aust. Soc. Anim. Prod. 15 (1984), 191-194, Scaramuzzi.
J. Reprod. Fert. 75 (1985), 121-131, McNatty et al.

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