Cyanoquanidine type III antiarrhythmic agents and use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514323, 546145, 546201, A61K 31445, A61K 3147, C07D40112

Patent

active

051323117

ABSTRACT:
Cyanoguanidines which have activity as Class III antiarrhythmic agents, acting by prolonging cardiac action potential repolarization. The invention further provides for compositions incorporating the compounds and methods of their use, as well as providing for pharmaceutically acceptable salts of the compounds.

REFERENCES:
patent: 4925850 (1990-05-01), George et al.
Cornu et al, Chemical Abstracts, vol. 105 (1986) No. 42652f.

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