Methods of treating disorders which cause conglutinin deficiency

Details Methods of treating disorders which cause conglutinin deficiency Methods of treating disorders which cause conglutinin deficiency

1989-11-27

1992-07-21

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424 858, 424 88, 514 2, 514 21, A61K 3746, A61K 3702

Patent

active

051322870

ABSTRACT:
Human conglutinin, polyclonal, and monoclonal antibodies raised against human conglutinin, and their uses in therapy and diagnosis are described.
Human conglutinin was obtained from human plasma by affinity chromatography with anti-bovine conglutinin antibody, has a relative molecular weight of 330 and 40 K unreduced and 66 K reduced as measured by SDS-PAGE, shows calcium-dependent and sugar inhibitable binding to complement-reacted immune complexes and zymosan, and immunological cross-reaction with anti-bovine conglutinin antibody.

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