Use of bendazac and its salts in the treatment of retinitis pigm

Details Use of bendazac and its salts in the treatment of retinitis pigm Use of bendazac and its salts in the treatment of retinitis pigm

1984-04-06

1985-11-19

Robinsion, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514912, A61K 3140

Patent

active

045542880

ABSTRACT:
It was discovered that bendazac, or (1-phenylmethyl-1H-indazol -3-yl)oxy acetic acid, when administered in a form suitable to obtain therapeutic tissue concentrations, determine an improvement in retinitis pigmentosa. The lysine salt of bendazac is well adapted for this use owing to its good oral absorption.

REFERENCES:
patent: Re27253 (1971-12-01), Palazzo
patent: 3625970 (1971-12-01), Ambrus
patent: 4282237 (1981-08-01), Silvestrini
patent: 4352813 (1982-10-01), Silvestrini et al.
patent: 4451477 (1984-05-01), Silvestrini et al.
The Lancet; Apr. 10, 1982, pp. 849-850-Testa et al.
Chem. Abst., 70:66559(r)(1969)-Silvestrini et al.
Chem. Abst., 99:152,048(d)(1983)-Silvestrini et al.

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