Process for O-demethylating fortimicins

Details Process for O-demethylating fortimicins Process for O-demethylating fortimicins

1979-03-29

1980-12-30

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 4, 568907, C07H 1522

Patent

active

042425034

ABSTRACT:
Described is a method of O-demethylating a fortimicin compound using hydriodic acid or tri-methylsilyiodide as an O-demethylating agent.

REFERENCES:
patent: 4124756 (1978-11-01), Martin et al.
Pigman, "The Carbohydrates", 1957, Academic Press, Inc., New York, N.Y., p. 368.
Noller, "Chemistry of Organic Compounds", 1965, W. B. Saunders Co., Philadelphia, Pa. pp. 161, 395 and 846.

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