Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-10-14
1988-08-23
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548411, 558341, 558406, 560 82, C07D20996, A61K 3140, C07B 4308, C07B 4306
Patent
active
047661410
ABSTRACT:
Spiro-succinimides are disclosed which are useful as aldose reductase inhibitors and as therapeutic agents for the treatment of complications arising from diabetes. Pharmaceutical compositions containing the spiro- compounds and a method of treating diabetic complications are also disclosed.
REFERENCES:
patent: 3821383 (1974-06-01), Sestanj et al.
patent: 3901916 (1975-08-01), Bastian et al.
patent: 3985888 (1976-10-01), Carr et al.
patent: 4117230 (1978-09-01), Sarges
Akers Lawrence C.
Berch Mark L.
Pfizer Inc.
Richardson Peter C.
Sheyka Robert F.
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