Salt of b-diethylaminoethyl ester of p-aminobenzoic acid with ac

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260 73R, 260 78A, 424278, C07D31906, A01N 928

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active

039431509

ABSTRACT:
A salt of .beta.-diethylaminoethyl ester of p-aminobenzoic acid with the acetal of polyvinyl alcohol and glyoxalic acid which has the formula: ##EQU1## wherein n is a degree of polymerization within the range of from 100 to 1,200; x is a degree of substitution within the range of from 5 to 30 mol.%. The compound has local anaesthetic properties.
A method of preparing said salt of .beta.-diethylaminoethyl ester of p-aminobenzoic acid and the acetal of polyvinyl alcohol and glyoxalic acid which comprises reacting the acetal of polyvinyl alcohol and glyoxalic acid with .beta.-diethylaminoethyl ester of p-aminobenzoic acid in an aqueous medium, followed by isolating the desired product from the resulting solution.

REFERENCES:
patent: 3560464 (1971-02-01), Toyoshima et al.
Richter, "Textbook of Organic Chemistry, " John Wiley & Sons, Inc., New York, (1952), Third Edition, p. 246.

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