Process for imidazo isoindoles

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2603433R, 260999, C07D 4934

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active

039431479

ABSTRACT:
Imidazo isoindoles, e.g. 5-(p-chlorophenyl)-5-hydroxy-2,3-dihydro-5H-imidazo[2,1a]isoindol, may be prepared by treating a corresponding 2-benzoyl benzoic acid with a substituted ethylene diamine, and treating a resulting intermediate first with concentrated acid and then with base. The products are active as anorexic agents.

REFERENCES:
patent: 3624101 (1971-11-01), Sulkowski
patent: 3657221 (1972-04-01), Sulkowski et al.
patent: 3763178 (1973-10-01), Sulkowski
Sulkowski et al., Journ. Org. Chem., Vol. 32, pp. 2180-2184, (1967).

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