Sulfonamide tetrazole ACAT inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548253, C07D25702

Patent

active

052390829

ABSTRACT:
Pharmaceutically useful compounds having ACAT inhibitory activity of the formula ##STR1## wherein R.sub.1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, a heteroaromatic group or a hydrocarbon group having from 1 to 18 carbon atoms; R.sub.2 and R.sub.3 are hydrogen, fluoro, alkyl, alkenyl, cycloalkyl, phenyl, substituted phenyl, a heteroaryl, or form a spiroalkyl group, and R.sub.4 is a hydrocarbon group having from 1 to 20 carbon atoms.

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patent: 4999345 (1991-03-01), Schmied et al.
patent: 5140038 (1992-08-01), Witte et al.

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