Compositions for photodynamic therapy

Details Compositions for photodynamic therapy Compositions for photodynamic therapy

1991-09-30

1993-08-24

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514 2, 514 43, 540145, A61K 3140, C07D48722

Patent

active

052389405

ABSTRACT:
Methods to prepare intermediates for the conjugation of active ingredients to hydrophilic carriers are described. The polyhydroxylated carriers are first derivatized to convert the hydroxyls to leaving groups and then reacted with an alkylene diamine in the presence of a reducing agent. The resulting derivatized carrier can then be coupled to substituents containing carboxyl groups in the presence of dehydrating agents.

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