BBM-1675c and d antitumor antibiotics

Details BBM-1675c and d antitumor antibiotics BBM-1675c and d antitumor antibiotics

1987-05-28

1990-05-01

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

435169, A61K 3574, C12P 104

Patent

active

049217003

ABSTRACT:
There is provided new antitumor antibiotic substances designated herein as BBM-1675C and BBM-1675D, said substances being produced by selective chemical hydrolysis of the bioactive components BBM-1675A.sub.1 (esperamicin A.sub.1) or BBM-1675A.sub.2 (esperamicin A.sub.2). The new antitumor antibiotics exhibit both antimicrobial activity and antitumor activity.

REFERENCES:
patent: 4594248 (1986-06-01), Wilton et al.
patent: 4661353 (1987-04-01), Wilton et al.
patent: 4675187 (1987-06-01), Konishi et al.

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