Method for treating burns

Drug – bio-affecting and body treating compositions – Lymphokine

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424DIG13, A61K 31745

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active

048791091

ABSTRACT:
In accordance with the present invention, a method and composition is provided for treating pathological hydrophobic interactions in biological fluids in which there is acute impairment of the circulation, especially the microcirculation. More particularly, the present invention relates to compositions and methods for treating circulatory diseases comprising using certain ethylene oxide-propylene oxide condensation surface active copolymers either alone or in combination other compounds.
Also contemplated in the present invention is a method for preserving a suspension of platelets. The method comprises adding an effective amount of a surface active copolymer.
The surface active copolymer can be an ethylene oxide-propylene oxide condensation product with the following general formula;

REFERENCES:
patent: 3450502 (1969-06-01), Hymes
patent: 3577522 (1971-05-01), Hymes
patent: 3590125 (1971-06-01), Hymes
patent: 3641240 (1972-02-01), Hymes et al.
patent: 3740421 (1973-06-01), Schmolka
patent: 3956259 (1976-05-01), Garcia et al.
patent: 3980772 (1976-09-01), Ginger et al.
patent: 4073886 (1978-02-01), Kohn
patent: 4186253 (1980-01-01), Yokoyama et al.
patent: 4609546 (1986-09-01), Hiratant
Schmolka, Irving R., "A Review of Block Polymer Surfactants", Journal of the American Oil Chemists Society, 54, No. 3, pp. 11-116 (1977).
Rodeheaver, G. T., "Pluronic F-68: A Promising New Skin Wound Cleanser", Ann Emerg Med., 9:11, pp. 572-576 (1980).
Moore, A. R., et al., "Reduction of Splenic Vascular Resistance During Profusion By Pluronic F-68", Journal of Surgical Research, vol. 8, No. 12, pp. 563-566 (1980).
Benner, K. U. et al., "Cold-Induced Platelet Aggregation In Vivo and Its Inhibition By A Nonionic Surface Active Substance", Thrombosis Research, vol. 2, pp. 331-342, (1973).
Hymes, A. C., "The Influence of an Industrial Surfactant Pluronic F-68, in the Treatment of Hemorrhagic Shock", Journal of Surg. Res., vol. 11, pp. 191-197 (1971).
Hoie, J., "Effects of Pluronic F68, Poloralkol, On Vascular Resistance In Vivo", Journal of Surgical Research, vol. 11, pp. 515-517, (1971).
Grover, F. L. et al., "A Nonionic Surfactant And Blood Viscosity", Arch. Surg., vol. 106, pp. 307-310, (1973).
Grover, Frederick L. et al., "The Effect of Pluronic F-68 On Circulatory Dynamics and Renal and Carotid Artery Flow During Hemorrhagic Shock", Journal of Surgical Research, vol. 17, pp. 30-35, (1974).
Ketchum, Lynn D. et al., "Experimental Use of Pluronic F-68 In Microvascular Surgery", Dept. of Surgery (Plastic), University of Kansas Medical Center, vol. 53, pp. 288-292, (1974).
Richard M. N., et al., "Effect of Lysine and Wetting Agents On Activated Plasminogen Solutions", Canadian Journal of Biochemistry and Physiology, vol. 41, pp. 211-217, 1963.
Technical Bulletin entitled "Performance Chemicals", describing Pluronic Block Copolymer Surfactants.
Technical Bulletin entitled "Pluronic Block Copolymer Surfactants".
Patent Cooperation Treaty International Search Report for PTC patent application No. PCT/US87/01067, File Reference No. 197220064.
Schmolka, Irving R., "Artificial Skin I. Preparation and Properties of Pluronic F-127 Gels for Treatment of Burns", J. Biomed. Mater. Res., vol. 6, pp. 571-582 (1972).

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