Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-12-23
1988-04-26
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540350, C07D48704, A61K 3140
Patent
active
047405074
ABSTRACT:
Compounds of formula (I): ##STR1## (wherein R.sup.1 is carboxy, --CONR.sup.4 R.sup.5, cyano or hydroxymethyl, and R.sup.2 and R.sup.3 are hydrogen, alkyl or substituted alkyl, R.sup.4 and R.sup.5 being hydrogen or a variety of groups) have good antibiotic activity and reduced renal toxicity.
REFERENCES:
patent: 4383946 (1983-05-01), Christenson et al.
patent: 4552873 (1985-11-01), Muyadera et al.
Hashimoto Toshihiko
Iino Kimio
Miyadera Tetsuo
Shibata Tomoyuki
Sugawara Shinichi
Rizzo Nicholas S.
Sankyo Company Limited
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